Foundation Medicine Publications

Learn more about the promise of comprehensive cancer genomic testing using next-generation sequencing from select publications.

  • Ross JS, Wang K, Sheehan CE, Boguniewicz AB, Otto G, Downing SR, Sun J, He J, Curran JA, Ali S, Yelensky R, Lipson D, Palmer G, Miller VA, Stephens PJ. Relapsed classic E-cadherin (CDH1) mutated invasive lobular breast cancer demonstrates a high frequency of HER2 (ERBB2) gene mutations. Clinical Cancer Research. 30 April 2013. Abstract.
  • Vignot S, Frampton GM, Soria JC, Yelensky R, Commo F, Brambilla C, Palmer G, Moro-Sibilot D, Ross JS, Cronin MT, André F, Stephens PJ, Lazar V, Miller VA, Brambilla E. Next-Generation Sequencing Reveals High Concordance of Recurrent Somatic Alterations Between Primary Tumor and Metastases From Patients With Non-Small-Cell Lung Cancer. Journal of Clinical Oncology. 29 April 2013. Abstract.
  • Drilon A, Wang L, Hasanovic A, Suehara Y, Lipson D, Stephens PJ, Ross J, Miller VA, Ginsberg MS, Zakowski MF, Kris MG, Ladanyi M, Rizvi NA. Response to Cabozantinib in Patients with RET Fusion-Positive Lung Adenocarcinomas. Cancer Discovery. 2013 Mar 26. Epub ahead of print.
  • Giulino-Roth L, et al.Targeted genomic sequencing of pediatric Burkitt lymphoma identifies recurrent alterations in antiapoptotic and chromatin-remodeling genes. Blood. 2012 Dec 20;120(26):5181-4. doi: 10.1182/blood-2012-06-437624. Abstract.
  • Beltran H, et al. Targeted Next-generation Sequencing of Advanced Prostate Cancer Identifies Potential Therapeutic Targets and Disease Heterogeneity. Eur Urol (2012), http://dx.doi.org/10.1016/j.eururo.2012.08.053 Abstract.
  • Peled N, Palmer G, Hirsch FR, Wynes MW, Ilouze M, Varella-Garcia M, Soussan-Gutman L, Otto GA, Stephens PJ, Ross JS, Cronin MT, Lipson D, Miller VA. Journal of Thoracic Oncology. Next-Generation Sequencing Identifies and Immunohistochemistry Confirms a Novel Crizotinib-Sensitive ALK Rearrangement in a Patient with Metastatic Non-Small-Cell Lung Cancer. 2012 Sep; 7(9):e14-6. (DOIi: 10.1097/JTO.0b013e3182614ab5). Abstract.
  • Lipson, D. et al. Nature Medicine. Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies. 2012 March 18(3):382-382. (DOI 10.1038/nm.2673). Publication.
  • Biomarkers in Medicine review article - Comprehensive next-generation cancer genome sequencing in the era of targeted therapy and personalized oncology. Publication.

 

 

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