- Cancer Type
- Sample Type
- Results Expected
What is FoundationOne?
FoundationOne is a validated comprehensive genomic profile (CGP) for solid tumors. The test is designed to provide physicians with clinically actionable information to guide treatment decisions for patients based on the genomic profile of their disease. Test results provide information about clinically significant alterations, potential targeted therapies, available clinical trials, and quantitative markers of response for immunotherapy.
FoundationOne is validated to detect all classes of genomic alterations in more than 300 cancer-related genes, including select introns from more than 25 genes often rearranged or altered in solid tumors.
select introns profiled
- A single test that detects all four classes of genomic alterations for solid tumors
- Results include microsatellite instability (MSI) and tumor mutational burden (TMB) measurements, which may help predict response to immunotherapy
- Typical median depth of coverage of >500x for sensitive and specific detection of alterations at low frequency‡