Genomic Testing
Order a Test
Submit an order form online, via fax, or by email.
If you have questions, we are here to help. Call Foundation Medicine Client Services at 888.988.3639 between 8:00 am ET and 8:00 pm ET, Monday through Friday. You can also send us an email and a representative will respond during regular business hours.
Ordering Overview
To order a Foundation Medicine test for a patient
Online Ordering
Order by Fax
- Download and complete the appropriate Test Requisition Form below. Follow instructions here for filling out the form.
- Fax the requisition form, along with the pathology report and insurance information, to 617.418.2290.
To order a specimen kit for any of our tests
Please contact a Client Services Representative at 888.988.3639 or client.services@foundationmedicine.com.
If sending a solid tumor specimen, Foundation Medicine will complete the rest of the specimen retrieval process. We will contact the pathologist and send a Specimen Collection Kit with instructions for sample procurement and shipment.
If sending peripheral blood or bone marrow aspirate, please follow the specimen preparation instructions for liquid specimens.
International Customers
To order, please visit rochefoundationmedicine.com or call +1 (888) 988-3639.
FoundationOne®CDx
FDA-Approved Broad Companion Diagnostic (CDx) for Solid Tumors with Medicare Coverage for Qualifying Patients1
FoundationOne CDx helps inform clinical decision making, with insights specific to each patient’s cancer. Results from a single tissue sample (FFPE) analyze multiple gene alterations and biomarkers to save time and tissue compared with sequential single-gene testing.
When submitting specimens to Foundation Medicine, please include the following items in the FoundationOne CDx Specimen Kit:
- Appropriate specimen per FoundationOne CDx Specimen Instructions labeled with two patient-specific identifiers
- Completed Test Requisition Form
- Copy of recent pathology/cytology reports
Clear, in-depth test results are typically available online or via fax in less than 14 days from receipt of specimen. Reports may help match cancer patients’ genomic profile with targeted therapies, immunotherapies, and clinical trials to expand treatment options.
1 Medicare and Medicare Advantage members have coverage of FoundationOne CDx in accordance with the Centers for Medicare and Medicaid Services (CMS) national coverage determination (NCD) criteria.
FoundationOne®Liquid
Patients with solid tumors can be tested using our liquid biopsy, FoundationOne Liquid, which requires two tubes of peripheral whole blood. When submitting specimens to Foundation Medicine, please include the following items in the FoundationOne Liquid Specimen Kit:
- Appropriate specimen per FoundationOne Liquid Specimen Collection Instructions (use only blood tubes provided in the kit)
- Completed Test Requisition Form
- Insurance information and available reports
Clear, in-depth test results are typically available online or via fax in less than 14 days from receipt of specimen. Reports may help match cancer patients’ genomic profiles with targeted therapies, immunotherapies, and clinical trials to expand treatment options.
Forms & Downloads
- Foundation Medicine Test Requisition Form
- Foundation Medicine Test Requisition Form Instructions
- FoundationOne Liquid Specimen Instructions
- FoundationOne Liquid Technical Specifications
- FoundationOne Liquid Mobile Phlebotomy FAQ for Physicians
- FoundationOne Liquid Mobile Phlebotomy FAQ for Patients
- Medicare Advanced Beneficiary Notice (ABN)
- ABN Information for Foundation Medicine Tests
FoundationOne®Heme
Patients with hematologic malignancies and sarcomas can be tested with FoundationOne Heme, which is performed on FFPE, peripheral whole blood or bone marrow aspirate specimens. When submitting specimens to Foundation Medicine, please include the following items in the FoundationOne Heme Specimen Kit:
- Appropriate specimen per FoundationOne Heme Specimen Collection Instructions, labeled with two patient-specific identifiers
- Completed Test Requisition Form
- Copy of recent pathology/cytology reports
Note for Bone Samples: Do not use strong acids to decalcify. Hydrochloric acid should be avoided; EDTA is recommended, and formic acid has mixed results. Place sample in decalcifying solution for minimal amount of time. Using a weaker acid and shorter time for decalcifying preserves the nucleic acid and increases likelihood for getting results on bone samples.
Clear, in-depth test results are typically available online or via fax in approximately 14 days from receipt of specimen. Reports may help match cancer patients’ genomic profile with targeted therapies, immunotherapies, and clinical trials to expand treatment options.
Forms & Downloads
- Foundation Medicine Test Requisition Form
- Foundation Medicine Test Requisition Form Instructions
- International Test Requisition Form
- FoundationOne Heme Specimen Instructions
- FoundationOne Heme Technical Specifications and Test Overview
- Medicare Advanced Beneficiary Notice (ABN)
- ABN Information for Foundation Medicine Tests
IHC Testing
Foundation Medicine offers two antibodies to test for PD-L1 expression:
- Dako 22C3
- Ventana SP142
PD-L1 Dako 22C3 pharmDx is a qualitative immunohistochemical assay using monoclonal mouse anti-PD-L1 clone 22C3 intended for use in the detection of PD-L1 protein in formalin-fixed, paraffin-embedded (FFPE) tissue from multiple tumor types in accordance with the approved product labeling.
PD-L1 Ventana SP142 is a qualitative immunohistochemical assay using rabbit monoclonal anti-PD-L1 clone SP142 intended for use in the assessment of the PD-L1 protein in formalin-fixed, paraffin-embedded (FFPE) tissue in accordance with the approved product labeling.
For tumors with no CDx indication, Foundation Medicine will perform PD-L1 testing using the Dako PD-L1 22C3 PharmDx assay.
For Urothelial Carcinoma (URC), if PD-L1 testing with the Ventana SP142 clone is preferred, please indicate that preference on the test requisition form, via online ordering, or contact our client services team at +1 888.988.3639 or by email at client.services@foundationmedicine.com.